1997.09-2001.06延边大学兽医专业学士
2001.09-2004.06延边大学预防兽医专业硕士
2006.04-2009.03日本带广畜产大学畜产卫生专业博士
4、工作经历
2004.07-2005.01延边大学助教
2005.02-2006.03日本带广畜产大学国立原虫病研究中心研究职员
2009.04-2011.09日本北海道大学人兽共患病研究中心博士后
2011.10-2020.12中国农业科学院哈尔滨兽医研究所副研究员
2021.01-至今中国农业科学院哈尔滨兽医研究所研究员
5、承担项目
(1)黑龙江省杰出青年基金：弓形虫顶质体跨膜转运分子机制，2022-2025
(2)黑龙江省重点研发专项：伴侣动物疫病防控制剂创制，2022-2025
(3)“十四五”国家重点研发计划项目：动物重要寄生虫的生长发育与寄生机制，2022-2025
(4)国家自然科学基金面上项目：弓形虫SNARE蛋白在分泌性细胞器生物发生过程中的作用机制研究，2018-2022
(5)“十三五”国家重点研发计划项目：畜禽重要胞内寄生原虫的寄生与免疫机制研究，2017-2022
(6)“十三五”国家重点研发计划项目：畜禽重要人兽共患寄生虫病源头防控与阻断技术研究，2017-2022
(7)国家自然科学基金青年基金项目：弓形虫氨基肽酶的功能解析及其作为药物靶点的可行性研究，2012-2015
(8)黑龙江省自然科学基金面上项目：弓形虫甲硫氨酸氨基肽酶药物靶点的鉴定，2015-2017
6、代表论文与著作
FuJ,ZhaoL,ChenH,CaoS,JiaH*.AnunconventionalSNAREcomplexmediatesexocytosisattheplasmamembraneandvesicularfusionattheapicalannuliinToxoplasmagondii.PLoSPathogens.2023,19(3):e1011288
CaoH,GuH,KangH*andJiaH*.DevelopmentofarapidreversegeneticssystemforfelinecoronavirusbasedonTARcloninginyeast.Front.Microbiol.2023,14:1141101.
FuJ,ZhaoL,PangY,ChenH,YamamotoH,ChenY,LiZ,MizushimaN,JiaH*.ApicoplastbiogenesismediatedbyATG8requirestheATG12-ATG5-ATG16LandSNAP29complexesinToxoplasmagondii.Autophagy.2023,19(4):1258-1276.
TheDissectionofSNAREsRevealsKeyFactorsforVesicularTraffickingtotheEndosome-likeCompartmentandApicoplastviatheSecretorySysteminToxoplasmagondii.CaoS.,YangJ.,FuJ.,ChenH.,JiaH*.mBio.2021,12(4):e0138021.通讯作者
Evolutionfromcovalentconjugationtonon-covalentinteractionintheubiquitin-likeATG12system.Pang,Y.,Yamamoto,H.,Sakamoto,H.,Oku,M.,Mutungi,J.K.,Sahani,M.H.,Kurikawa,Y.,Kita,K.,Noda,N.N.&Sakai,Y.,Jia,H.*,Mizushima,N*.Naturestructural&molecularbiology,2019,26:289-296,共同通讯作者
TgMAP1cisinvolvedinapicoplastbiogenesisinToxoplasmagondii.Zheng,J.,Su,W.,Cao,S.,Zhang,Z.,Du,C.,Jia,H.*InternationalJournalforParasitology,2020,50:487-499,通讯作者
HydroxylamineandCarboxymethoxylamineCanInhibitToxoplasmagondiiGrowththroughanAspartateAminotransferase-IndependentPathway,Li,J.,Guo,H.,Galon,E.M.,Gao,Y.,Lee,S.,Liu,M.,Li,Y.,Ji,S.,Jia,H*.,Xuan，X*.,AntimicrobAgentsChemother,2020,64(3):e01889-19.共同通讯作者
GABARAPL2IsCriticalforGrowthRestrictionofToxoplasmagondiiinHeLaCellsTreatedwithGammaInterferon.Zhang,Z.,Gu,H.,Li,Q.,Zheng,J.,Cao,S.,Weng,C.,Jia,H.*InfectionandImmunity,2020,88:e00054-20,通讯作者
TheSec1/Munc18‐likeproteinsTgSec1andTgVps45playpivotalrolesinassemblyofthepellicleandsub‐pelliclenetworkinToxoplasmagondii.Cao,S.,Chen,H.,Liang,X.,Fu,J.,Wang,S.,Zheng,J.,Zhang,Z.,Pang,Y.,Wang,J.&Shen,B.,Jia,H.*.Molecularmicrobiology,2019,113:208-221,通讯作者
TranslationallycontrolledtumorproteinisrequiredforthefastgrowthofToxoplasmagondiiandmaintenanceofitsintracellulardevelopment.Zheng,J.,Chen,Y.,Li,Z.,Cao,S.,Zhang,Z.&Jia,H.*FASEBJ,2018,32:906-919,通讯作者
KnockoutofleucineaminopeptidaseinToxoplasmagondiiusingCRISPR/Cas9.Zheng,J.,Jia,H.*,&Zheng,Y.InternationalJournalforParasitology,2015,45:141-148,通讯作者
CharacterizationofaspartylaminopeptidasefromToxoplasmagondii.Zheng,J.,Cheng,Z.,Jia,H.*&Zheng,Y.SciRep,2016,6:34448,通讯作者
ToxoplasmagondiiClpfamilyprotein:TgClpB1playsacrucialroleinthermotolerance.Cao,S.,NaliDu,Chen,H.,Pang,Yu.,Zhang,Z.,Zheng,J.Jia,H.*Oncotarget.2017,8:86117-86129.
Wang,M.,Cao,S.,Du,N.,Fu,J.,Li,Z.,Jia,H.＊,MingxinSong*.ThemovingjunctionproteinRON4,althoughnotcritical,facilitateshostcellinvasionandstabilizesMJmembers.Parasitology.2017,144(11):1490-1497
FunctionalcharacterizationofX-prolylaminopeptidasefromToxoplasmagondii.Yang,M.,Zheng,J.,Jia,H.,*,Song,M.*Parasitology.2016,143(11):1443-9.
Meng,X.,,Zheng,J.,He,X.,Jia,H.*,Zhang,Y.*FirstcharacterizationinChinaofEncephalitozooncuniculiinthebluefox(Alopexlagopus).JEukaryotMicrobiol.2014,61(6):580-5.
Evaluationofsporewallprotein1asanalternativeantigenforthediagnosisofEncephalitozooncuniculiinfectionoffarmedfoxesusinganenzyme-linkedimmunosorbentassay.Meng,X.,Zheng,J.,Gao,Y.,Zhang,Y*.&Jia,H*.VeterinaryParasitology,2014,203:331-334,通讯作者
Jia,H.,Nishikawa,Y.,Luo,Y.,Yamagishi,J.,Sugimoto,C.,Xuan,X.,CharacterizationofaleucineaminopeptidasefromToxoplasmagondii.MolBiochemParasitol170,1-6.
Jia,H.,Zhou,J.,Ikadai,H.,Matsuu,A.,Suzuki,H.,Igarashi,I.,Fujisaki,K.,Xuan,X.,2006.Identificationofanovelgeneencodingasecretedantigen1ofBabesiagibsoniandevaluationofitsuseinserodiagnosis.AmJTropMedHyg75,843-850.
Jia,H.,Liao,M.,Lee,E.,Nishikawa,Y.,Inokuma,H.,Ikadai,H.,Matsuu,A.,Igarashi,I.,Xuan,X.,2007.DevelopmentofanimmunochromatographictestwithrecombinantBgSA1forthediagnosisofBabesiagibsoniinfectionindogs.ParasitolRes100,1381-1384.
Jia,H.,Terkawi,M.A.,Aboge,G.O.,Goo,Y.K.,Zhou,J.,Lee,E.G.,Nishikawa,Y.,Igarashi,I.,Fujisaki,K.,Xuan,X.,2008.Babesiagibsoni:identificationofanimmunodominant,interspersedrepeatantigen.ExpParasitol118,146-149.
Jia,H.,Aboge,G.O.,Terkawi,M.A.,Goo,Y.K.,Nishikawa,Y.,Kuriki,K.,Lee,K.K.,Jang,H.K.,Kim,S.,Fujisaki,K.,Xuan,X.,2009.GeneticdiversityoftwoselectedantigenlociinBabesiagibsoniAsiangenotypeobtainedfromJapanandJejuislandofSouthKorea.VetParasitol162,142-146.
Jia,H.,Terkawi,M.A.,Aboge,G.O.,Goo,Y.K.,Luo,Y.,Li,Y.,Yamagishi,J.,Nishikawa,Y.,Igarashi,I.,Sugimoto,C.,Fujisaki,K.,Xuan,X.,2009.CharacterizationofaleucineaminopeptidaseofBabesiagibsoni.Parasitology136,945-952.
Jia,H.,Terkawi,M.A.,Aboge,G.O.,Goo,Y.K.,Ma,L.,Zhou,J.,Nishikawa,Y.,Igarashi,I.,Fujisaki,K.,Xuan,X.,2009.Identificationofsecretedantigen3fromBabesiagibsoni.ClinVaccineImmunol16,944-948.