硬件：曙光高性能计算集群(总计160个计算核心、804G内存、50T存储)、DELLPowerEdgeR900计算服务器2台、DELLPowerEdgeR300计算服务器1台、IBM图形工作站2台等；
软件：生物信息学流程处理平台PipelinePilot(StudentEdition)和InforSense、药物设计软件包sybyl及MOE、代谢网络构建分析PathwayStudio，等；中药化学(TCMD)、大英农药杀虫剂数据库(BCPC)、NCI、Zinc等数据库。
代表性论文：
Hong-FangJi*,Hong-YuZhang*.β-sheetconstitutionofprionproteins.TrendsBiochem.Sci.,2010,35:129-134.(SCI,IF:11.572)
Hong-YuZhang*,Ling-LingChen,Xue-JuanLi,JianZhang.Evolutionaryinspirationsfordrugdiscovery.TrendsPharmacol.Sci.,2010,31:443-448.(SCI,IF:9.064)
De-XinKong,Ying-YingJiang,Hong-YuZhang*.Marinenaturalproductsassourcesofnovelscaffolds:achievementandconcern.DrugDiscov.Today,2010,15:884-886.(SCI,IF:6.630)
NaGao,Ling-LingChen*,Hong-FangJi,WeiWang,Ji-WeiChang,BeiGao,LinZhang,Shi-CuiZhang,Hong-YuZhang*.DIGAP-adatabaseofimprovedgeneannotationforphytopathogens.BMCGenomics,2010,11:54.(SCI,IF:3.926)
Hong-YuZhang*,Xue-JuanLi,NaGao,Ling-LingChen.AntioxidantsusedbyDeinococcusradioduransandimplicationsforantioxidantdrugdiscovery.Nat.Rev.Microbiol.,2009,7:476.(SCI,IF:14.310)
De-XinKong,Xue-juanLi,Hong-yuZhang*.WhereisthehopefordrugdiscoveryLethistorytellthefuture.DrugDiscov.Today,2009,14:115-119.(SCI,IF:6.630,ScienceDirectTop25HottestArticles)
De-XinKong,WeiRen,WeiLu,Hong-YuZhang*.DoBiologicallyRelevantCompoundsHaveMoreChanceToBeDrugsJ.Chem.Info.Model.,2009,49:2376-2381.(SCI,IF:3.882)
Ling-LingChen*,Bin-GuangMa,NaGao.ReannotationofhypotheticalORFsinplantpathogenErwiniacarotovorasubsp.atrosepticaSCRI1043.FEBSJ.,2008,275:198-206.(SCI,IF:3.139)
Hong-FangJi,De-XinKong,LiangShen,Ling-LingChen,Bin-GuangMa,Hong-YuZhang*.Distributionpatternsofsmall-moleculeligandsintheproteinuniverseandimplicationsfororiginoflifeanddrugdiscovery.GenomeBiol.,2007,8:R176.(SCI,IF:6.153)
Ling-LingChen*.Identificationofgenomicislandsinsixplantpathogens.Gene,2006,374:134-141.(SCI,IF:2.578)